TRIB2 SAFEGUARDS NAIVE T CELL HOMEOSTASIS DURING AGING

TRIB2 safeguards naive T cell homeostasis during aging

Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, Tote Bag suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells and counteracts quiescence exit by suppressing AKT activation.TRIB2 deficiency increases AKT

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Letters commenting on published articles: Last but not the least

As a part of the post-publication peer review, readers can send comment letters to a Tote Bag journal on the articles it has published.Such letters critically comment on the content of the related article.They allow the readers to see the messages of the article in the context of the criticisms, give the authors of the concerned article an opportun

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